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5.3.1 Transcriptomics methodologies Two main approaches for transcriptomics are microarray and RNA-sequencing (RNA-Seq)

All data are presented as the mean standard error of the mean (SEM)

However, as with any treatment, there may be minor side effects like nausea or dizziness, but these are usually temporary

The DDX3X degrader J10 shows enhanced cytotoxic activity relative to RK-33 In our pursuit of evaluating DDX3X as a therapeutic target in lung cancer, we conceived twelve potential heterobifunctional DDX3X degraders using Proteolysis Targeting Chimeras (PROTACs) technology [44], which leverage the ubiquitin-proteasome system to induce DDX3X degradation (Fig